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Christopher R Chitambar Selected Research

gallium nitrate

1/2018Gallium Complexes as Anticancer Drugs.
3/2015Gallium maltolate inhibits human cutaneous T-cell lymphoma tumor development in mice.
3/2013Iron-targeting antitumor activity of gallium compounds and novel insights into triapine(®)-metal complexes.
6/2012Gallium-containing anticancer compounds.
1/2010Medical applications and toxicities of gallium compounds.
9/2008Role of oxidative stress in the induction of metallothionein-2A and heme oxygenase-1 gene expression by the antineoplastic agent gallium nitrate in human lymphoma cells.
9/2007Development of gallium compounds for treatment of lymphoma: gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma cell resistance to gallium nitrate.
2/2007Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate.
11/2006Gallium-induced cell death in lymphoma: role of transferrin receptor cycling, involvement of Bax and the mitochondria, and effects of proteasome inhibition.
11/2004Apoptotic mechanisms of gallium nitrate: basic and clinical investigations.
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Christopher R Chitambar Research Topics

Disease

25Neoplasms (Cancer)
01/2022 - 04/2003
10Lymphoma (Lymphomas)
07/2018 - 04/2003
9Breast Neoplasms (Breast Cancer)
03/2021 - 11/2006
7Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2018 - 05/2004
6Glioblastoma (Glioblastoma Multiforme)
04/2020 - 04/2017
5Urinary Bladder Neoplasms (Bladder Cancer)
03/2013 - 04/2003
4Pathologic Complete Response
01/2022 - 10/2002
3Brain Neoplasms (Brain Tumor)
04/2020 - 04/2017
3B-Cell Lymphoma (Lymphoma, B Cell)
03/2015 - 10/2002
2Triple Negative Breast Neoplasms
01/2022 - 05/2019
2Cardiotoxicity
05/2019 - 05/2002
2Leukemia
07/2018 - 07/2002
2Colorectal Neoplasms (Colorectal Cancer)
12/2017 - 04/2017
2Hypercalcemia (Milk Alkali Syndrome)
11/2004 - 04/2003
2B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
04/2003 - 12/2002
2Multiple Myeloma
04/2003 - 12/2002
1Glioma (Gliomas)
01/2022
1Necrosis
04/2020
1Ductal Carcinoma
04/2020
1Osteosarcoma (Osteogenic Sarcoma)
07/2018
1Leukoencephalopathies
07/2018
1Noninfiltrating Intraductal Carcinoma (DCIS)
06/2018
1Carcinogenesis
12/2017
1Medulloblastoma
04/2017
1Rhabdoid Tumor (Rhabdoid Tumors)
04/2017
1Fatigue
10/2016
1Obesity
10/2016
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
03/2015
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
07/2010
1Psoriasis (Pustulosis Palmaris et Plantaris)
06/2007
1Hemochromatosis (Bronze Diabetes)
11/2006
1Iron Overload
03/2005

Drug/Important Bio-Agent (IBA)

16GalliumIBA
01/2018 - 04/2003
15IronIBA
01/2022 - 05/2002
13gallium nitrateFDA Link
01/2018 - 04/2003
10MetalsIBA
01/2018 - 04/2003
8Antineoplastic Agents (Antineoplastics)IBA
01/2018 - 11/2004
6Pharmaceutical PreparationsIBA
12/2017 - 05/2002
5Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
04/2020 - 11/2004
5Doxorubicin (Adriamycin)FDA LinkGeneric
01/2012 - 05/2002
4gallium maltolateIBA
04/2020 - 09/2007
4SaltsIBA
01/2018 - 04/2003
4Transferrin Receptors (Transferrin Receptor)IBA
11/2006 - 05/2004
3Biomarkers (Surrogate Marker)IBA
01/2022 - 03/2013
3Hormones (Hormone)IBA
04/2020 - 04/2012
3Methotrexate (Mexate)FDA LinkGeneric
12/2019 - 07/2002
3Chelating AgentsIBA
05/2019 - 05/2002
3Estrogen ReceptorsIBA
06/2018 - 04/2012
3Transferrin (beta 2 Transferrin)IBA
01/2018 - 05/2004
3Acid CeramidaseIBA
12/2017 - 04/2017
3Proteins (Proteins, Gene)FDA Link
12/2017 - 02/2007
33-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA
03/2013 - 04/2008
2Androgen Receptors (Androgen Receptor)IBA
01/2022 - 04/2020
2Metformin (Glucophage)FDA LinkGeneric
04/2020 - 05/2019
2Progesterone Receptors (Progesterone Receptor)IBA
06/2018 - 06/2016
2carmofurIBA
12/2017 - 04/2017
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2012 - 10/2002
2CalciumIBA
01/2010 - 04/2003
2Biological ProductsIBA
02/2004 - 10/2002
2Rituximab (Mabthera)FDA Link
02/2004 - 10/2002
2Vincristine (Oncovin)FDA LinkGeneric
10/2002 - 07/2002
1MicroRNAs (MicroRNA)IBA
03/2021
1Keratin-18 (Keratin 18)IBA
04/2020
1DeferasiroxFDA Link
05/2019
1Dexrazoxane (Zinecard)FDA LinkGeneric
05/2019
1AntimetabolitesIBA
07/2018
1RNA (Ribonucleic Acid)IBA
05/2018
1ApoferritinsIBA
01/2018
1Citric Acid (Citrate)FDA LinkGeneric
01/2018
1Iron-Binding ProteinsIBA
01/2018
1Temozolomide (Temodar)FDA LinkGeneric
12/2017
1CytokinesIBA
03/2015
1Coordination ComplexesIBA
03/2013
1ThiosemicarbazonesIBA
03/2013
1Estrogens (Estrogen)FDA Link
04/2012
1Mitogen-Activated Protein KinasesIBA
04/2012
1AnthracyclinesIBA
01/2012
1Epirubicin (Ellence)FDA LinkGeneric
01/2012
1taxaneIBA
01/2012
1Docetaxel (Taxotere)FDA Link
01/2012
1EnzymesIBA
01/2011
1Drug CombinationsIBA
07/2010
1Bortezomib (Velcade)FDA Link
07/2010
1Heme Oxygenase-1IBA
09/2008
1Immunosuppressive Agents (Immunosuppressants)IBA
06/2007
1efalizumab (Raptiva)FDA Link
06/2007
1ZincIBA
02/2007
1DNA (Deoxyribonucleic Acid)IBA
02/2007
1MetallothioneinIBA
02/2007
1Transcription Factor MTF-1IBA
02/2007
1Proteasome Endopeptidase Complex (Proteasome)IBA
11/2006
1Ferritins (Ferritin)IBA
03/2005

Therapy/Procedure

8Therapeutics
01/2022 - 03/2013
5Drug Therapy (Chemotherapy)
05/2019 - 10/2002
3Neoadjuvant Therapy
01/2022 - 01/2012
2Adjuvant Chemotherapy
09/2018 - 10/2016
1Segmental Mastectomy (Lumpectomy)
06/2018
1TEC protocol
01/2012
1Combination Drug Therapy (Combination Chemotherapy)
07/2010
1Aftercare (After-Treatment)
06/2007